Recombinant Anti-PLSCR3 antibody [EPR9242] (ab137128)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR9242] to PLSCR3
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-PLSCR3 antibody [EPR9242]
See all PLSCR3 primary antibodies -
Description
Rabbit monoclonal [EPR9242] to PLSCR3 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide within Human PLSCR3 aa 1-100 (N terminal). The exact sequence is proprietary.
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Positive control
- Human fetal lung and BxPC 3 lysates.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20ºC. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR9242 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab137128 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/10000. Predicted molecular weight: 32 kDa.
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Notes |
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WB
1/1000 - 1/10000. Predicted molecular weight: 32 kDa. |
Target
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Function
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. -
Tissue specificity
Expressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine and peripheral blood lymphocytes. Not detected in testis, brain and liver. -
Sequence similarities
Belongs to the phospholipid scramblase family. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 57048 Human
- Entrez Gene: 70310 Mouse
- Entrez Gene: 360549 Rat
- Omim: 607611 Human
- SwissProt: Q9NRY6 Human
- SwissProt: Q9JIZ9 Mouse
- SwissProt: Q6QBQ4 Rat
- Unigene: 534591 Human
see all -
Alternative names
- Ca(2+)-dependent phospholipid scramblase 3 antibody
- Phospholipid scramblase 3 antibody
- PL scramblase 3 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab137128 has been referenced in 2 publications.
- Chao H et al. Cardiolipin-Dependent Mitophagy Guides Outcome after Traumatic Brain Injury. J Neurosci 39:1930-1943 (2019). PubMed: 30626699
- Luévano-Martínez LA & Kowaltowski AJ Topological characterization of the mitochondrial phospholipid scramblase 3. FEBS Lett 591:4056-4066 (2017). PubMed: 29171872