Overview

  • Product name

    Anti-PLSCR3 antibody [EPR9242]
    See all PLSCR3 primary antibodies
  • Description

    Rabbit monoclonal [EPR9242] to PLSCR3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human PLSCR3 aa 1-100 (N terminal). The exact sequence is proprietary.

  • Positive control

    • Human fetal lung and BxPC 3 lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab137128 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 32 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function

      May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
    • Tissue specificity

      Expressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine and peripheral blood lymphocytes. Not detected in testis, brain and liver.
    • Sequence similarities

      Belongs to the phospholipid scramblase family.
    • Cellular localization

      Membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • Ca(2+)-dependent phospholipid scramblase 3 antibody
      • Phospholipid scramblase 3 antibody
      • PL scramblase 3 antibody
      • PLS3 antibody
      • PLS3_HUMAN antibody
      • Plscr3 antibody
      see all

    Images

    • All lanes : Anti-PLSCR3 antibody [EPR9242] (ab137128) at 1/1000 dilution

      Lane 1 : Human fetal lung lysate
      Lane 2 : BxPC 3 lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 32 kDa

    References

    This product has been referenced in:

    • Luévano-Martínez LA & Kowaltowski AJ Topological characterization of the mitochondrial phospholipid scramblase 3. FEBS Lett 591:4056-4066 (2017). Read more (PubMed: 29171872) »
    See 1 Publication for this product

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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