Key features and details
- Selective, irreversible presynaptic voltage-gated Ca2+ channel blocker. Potent neurotoxin.
- CAS Number:
- Purity: > 99%
- Soluble in water
- Form / State: Solid
- Source: Plectreurys tristis
Product namePLTX-II, presynaptic voltage-gated Ca2+ channel blocker
DescriptionSelective, irreversible presynaptic voltage-gated Ca2+ channel blocker. Potent neurotoxin.
Biological descriptionSelective, irreversible presynaptic voltage-gated Ca2+ channel blocker. Potent neurotoxin. Selective exocytosis inhibitor. Shows insecticidal effects in vivo.
SequenceADCSATGDTCDHTKKCCDDCYTCRCGTPWGANCRCDYYKARCDT (Modifications: C-terminal amide; Thr-44 = O-palmitoyl; Disulfide bonds: 3-17, 10-23, 16-35, 20-42, 25-33)
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab145555 has not yet been referenced specifically in any publications.