Overview

  • Product name

    (plusminus)-Bisoprolol hemifumarate, beta1 antagonist
  • Description

    Selective β1 antagonist
  • Biological description

    Selective β1 antagonist (Ki = 22.4 nM). Antihypertensive agent.
  • Purity

    > 99%
  • CAS Number

    104344-23-2
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • de Man FS  et al. Bisoprolol delays progression towards right heart failure in experimental pulmonary hypertension. Circ Heart Fail 5:97-105 (2012). Read more (PubMed: 22157723) »
  • Hoffmann C  et al. Comparative pharmacology of human beta-adrenergic receptor subtypes--characterization of stably transfected receptors in CHO cells. Naunyn Schmiedebergs Arch Pharmacol 369:151-9 (2004). Read more (PubMed: 14730417) »
  • Schnabel P  et al. Binding properties of beta-blockers at recombinant beta1-, beta2-, and beta3-adrenoceptors. J Cardiovasc Pharmacol 36:466-71 (2000). Read more (PubMed: 11026647) »
  • Smith C & Teitler M Beta-blocker selectivity at cloned human beta 1- and beta 2-adrenergic receptors. Cardiovasc Drugs Ther 13:123-6 (1999). Read more (PubMed: 10372227) »

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