• Product name
    Anti-PLVAP antibody [MECA-32]
    See all PLVAP primary antibodies
  • Description
    Rat monoclonal [MECA-32] to PLVAP
  • Host species
  • Specificity
    This antibody is specific to PLVAP.
  • Tested applications
    Suitable for: Flow Cyt, IP, IHC-Fr, ICC, WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Tissue/ cell preparation: Mouse lymph node stromal cells.

  • Positive control
    • Embryonic and adult mouse endothelial cell surfaces with the exceptions of cardiac, skeletal muscle and brain.



Our Abpromise guarantee covers the use of ab27853 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 1µg for 106 cells.

ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.


IP Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

Acetone fixed sections.

ICC Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Detects a band of approximately 50 - 55 kDa (predicted molecular weight: 51 kDa).


  • Function
    Involved in the formation of stomatal and fenestral diaphragms of caveolae. May function in microvascular permeability.
  • Tissue specificity
    Expressed in lung, kidney, heart, aorta, placenta, muscle, pituitary gland, adrenals, mammary gland, bladder, lymph node, bone marrow, trachea, digestive tract, liver and tumor-associated endothelium.
  • Cellular localization
    Cell membrane. Membrane > caveola. Cytoplasm > perinuclear region. Membrane-associated protein of caveolae. Found in fenestral and stomatal diaphragms in fenestrated endothelia and transendothelial channels. Also colocalized with CAV1 in perinuclear region.
  • Information by UniProt
  • Database links
  • Alternative names
    • FELS antibody
    • Fenestrated endothelial linked structure protein antibody
    • Fenestrated endothelial-linked structure protein antibody
    • gp68 antibody
    • Hypothetical protein DKFZp667O074 antibody
    • Meca 32 antigen antibody
    • MECA32 antigen antibody
    • Panendothelial cell antigen antibody
    • Plasmalemma vesicle associated protein antibody
    • Plasmalemma vesicle protein 1 antibody
    • Plasmalemma vesicle-associated protein antibody
    • Plvap antibody
    • PLVAP_HUMAN antibody
    • PV 1 antibody
    • PV-1 antibody
    • PV1 antibody
    • PV1 protein antibody
    see all


This product has been referenced in:
  • Englinger B  et al. Intrinsic fluorescence of the clinically approved multikinase inhibitor nintedanib reveals lysosomal sequestration as resistance mechanism in FGFR-driven lung cancer. J Exp Clin Cancer Res 36:122 (2017). Read more (PubMed: 28882160) »
  • Wang XL  et al. VEGFR-3 blocking deteriorates inflammation with impaired lymphatic function and different changes in lymphatic vessels in acute and chronic colitis. Am J Transl Res 8:827-41 (2016). IHC-Fr ; Mouse . Read more (PubMed: 27158372) »

See all 7 Publications for this product

Customer reviews and Q&As

Thank you for your patience.

For ab27853, it is as I had thought in my last email.The application was added based on publications showing that [MECA-32] has worked in IHC-Fr, e.g.

"The Adnectin CT-322 is a novel VEGF receptor ...

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Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products.

I am sorry the product ab2350 did not perform as stated on the datasheet and for the inconvenienc...

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Thank you for contacting us. While I am unaware of any references describingACVRL1 expression in tumors, the human protein atlas (linked below) does show that "distinct cytoplasmic staining with a granular pattern was observed in thyroid cancers, ...

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