Anti-PNPLA8 antibody (ab154233)
Key features and details
- Rabbit polyclonal to PNPLA8
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-PNPLA8 antibody
See all PNPLA8 primary antibodies -
Description
Rabbit polyclonal to PNPLA8 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 444-680 of Human PNPLA8 (UniProt: Q9NP80).
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Positive control
- Jurkat whole cell lysate (ab7899).
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab154233 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 88 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 88 kDa. |
Target
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Function
Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids. -
Tissue specificity
Expressed in parenchymal tissues including heart, skeletal muscle, placenta, brain, liver and pancreas. Also expressed in bronchial epithelial cells and kidney. Highest expression is observed in skeletal muscle and heart. -
Sequence similarities
Contains 1 patatin domain. -
Cellular localization
Endoplasmic reticulum membrane. Golgi apparatus membrane. Cytoplasm > perinuclear region. - Information by UniProt
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Database links
- Entrez Gene: 50640 Human
- Entrez Gene: 67452 Mouse
- Omim: 612123 Human
- SwissProt: Q9NP80 Human
- SwissProt: Q8K1N1 Mouse
- Unigene: 617340 Human
- Unigene: 732217 Human
- Unigene: 54126 Mouse
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Alternative names
- Calcium-independent phospholipase A2-gamma antibody
- Intracellular membrane associated calcium independent phospholipase A2 gamma antibody
- Intracellular membrane-associated calcium-independent phospholipase A2 gamma antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab154233 has been referenced in 1 publication.
- Mendham AE et al. Exercise training improves mitochondrial respiration and is associated with an altered intramuscular phospholipid signature in women with obesity. Diabetologia N/A:N/A (2021). PubMed: 33770195