The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa.
Participates in DNA repair and in chromosomal DNA replication.
Belongs to the DNA polymerase type-B family.
The DNA polymerase activity domain resides in the N-terminal half of the protein, while the C-terminus is necessary for complexing subunits B and C. The C-terminus may also regulate the catalytic activities of the enzyme.
Phosphorylated upon DNA damage, probably by ATM or ATR.