Overview

  • Product name

  • Description

    Rabbit polyclonal to POLR2I
  • Host species

    Rabbit
  • Specificity

    ab192407 detects endogenous levels of POLR2I protein.

  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human POLR2I. The exact sequence is proprietary.
    Database link: P36954

  • Positive control

    • A549, NIH 3T3 and PC12 whole cell lysates.
  • General notes

     This product was previously labelled as RNA Polymerase II p14.5

     

Properties

Applications

Our Abpromise guarantee covers the use of ab192407 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 15 kDa.

Target

  • Function

    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template.
  • Sequence similarities

    Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
    Contains 1 TFIIS-type zinc finger.
  • Post-translational
    modifications

    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • DNA directed RNA polymerase II 14.5 kDa polypeptide antibody
    • DNA directed RNA polymerase II polypeptide I antibody
    • DNA directed RNA polymerase II subunit I antibody
    • DNA directed RNA polymerase II subunit RPB9 antibody
    • DNA-directed RNA polymerase II subunit I antibody
    • DNA-directed RNA polymerase II subunit RPB9 antibody
    • hRPB14.5 antibody
    • POLR2I antibody
    • Polymerase (RNA) II (DNA directed) polypeptide I 14.5kDa antibody
    • RNA polymerase II 14.5 kDa subunit antibody
    • RNA polymerase II subunit B9 antibody
    • RPB14.5 antibody
    • RPB9 antibody
    • RPB9_HUMAN antibody
    see all

Images

  • All lanes : Anti-POLR2I antibody (ab192407)

    Lane 1 : A549 whole cell lysate
    Lane 2 : NIH 3T3 whole cell lysate
    Lane 3 : PC12 whole cell lysate

    Predicted band size: 15 kDa

References

ab192407 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab192407.
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