Key features and details
- Rabbit polyclonal to Polymeric immunoglobulin receptor/PIGR
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Polymeric immunoglobulin receptor/PIGR antibody
See all Polymeric immunoglobulin receptor/PIGR primary antibodies
DescriptionRabbit polyclonal to Polymeric immunoglobulin receptor/PIGR
SpecificityBLAST analysis of the peptide immunogen showed no homology with other Human proteins.
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Gorilla, Orangutan
Synthetic peptide corresponding to Human Polymeric immunoglobulin receptor/PIGR (internal sequence).
Database link: NP_002635.2
- Human small intestine tissue.
Previously labelled as PIGR.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C.
Storage bufferPreservative: 0.1% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab140937 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 1.25 - 2.5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.|
FunctionThis receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
Sequence similaritiesContains 5 Ig-like V-type (immunoglobulin-like) domains.
modificationsN-glycosylation is not necessary for Ig binding.
Cellular localizationSecreted and Cell membrane.
- Information by UniProt
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ab140937 has not yet been referenced specifically in any publications.