Overview

  • Product name

    Pomalidomide, Antiangiogenic agent
  • Description

    Inhibits LPS-induced TNF-α. Antiangiogenic agent.
  • Biological description

    Inhibits LPS-induced TNF-α. Antiangiogenic agent. Thalidomide (ab120032) derivative. Shows antiproliferative and immunomodulatory effects in vivo. Orally active.
  • Purity

    > 99%
  • CAS Number

    19171-19-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Zhu YX  et al. Molecular mechanism of action of immune-modulatory drugs thalidomide, lenalidomide and pomalidomide in multiple myeloma. Leuk Lymphoma 54:683-7 (2013). Read more (PubMed: 22966948) »
  • Henry JY  et al. Enhanced cross-priming of naive CD8+ T cells by dendritic cells treated by the IMiDs® immunomodulatory compounds lenalidomide and pomalidomide. Immunology 139:377-85 (2013). Read more (PubMed: 23374145) »
  • D'Amato RJ  et al. Pomalidomide is strongly antiangiogenic and teratogenic in relevant animal models. Proc Natl Acad Sci U S A 110:E4818 (2013). Read more (PubMed: 24302770) »

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