Overview

  • Product name

    Potassium canrenoate, Aldosterone antagonist
  • Description

    Aldosterone antagonist
  • Biological description

    Aldosterone antagonist. Metabolized to canrenone. Antiarrhythmic and diuretic activities. Produces genotoxic effects in vitro.
  • Purity

    > 98%
  • CAS Number

    2181-04-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Martelli A  et al. Genotoxicity testing of potassium canrenoate in cultured rat and human cells. Mutagenesis 14:463-72 (1999). Read more (PubMed: 10473649) »
  • Cook CS  et al. Difference in metabolic profile of potassium canrenoate and spironolactone in the rat: mutagenic metabolites unique to potassium canrenoate. Arch Toxicol 61:201-12 (1988). Read more (PubMed: 3355365) »
  • Armanini D  et al. In-vivo metabolites of spironolactone and potassium canrenoate: determination of potential anti-androgenic activity by a mouse kidney cytosol receptor assay. Clin Endocrinol (Oxf) 23:341-7 (1985). Read more (PubMed: 4064345) »

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