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ab32104 has been referenced in 35 publications.

  • Yuan C  et al. OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing ß-amyloid clearance in APP/PS1 mice. Biochim Biophys Acta Mol Basis Dis 1865:161-180 (2019). PubMed: 30389579
  • da Silva RA  et al. Laminar shear stress-provoked cytoskeletal changes are mediated by epigenetic reprogramming of TIMP1 in human primary smooth muscle cells. J Cell Physiol 234:6382-6396 (2019). PubMed: 30238981
  • Williams AP  et al. Investigation of PP2A and Its Endogenous Inhibitors in Neuroblastoma Cell Survival and Tumor Growth. Transl Oncol 12:84-95 (2019). PubMed: 30286326
  • Tang S  et al. Hydrogen peroxide redistributes the localization of protein phosphatase methylesterase 1. Life Sci 213:166-173 (2018). PubMed: 30340029
  • Huang YH  et al. SET Overexpression is Associated with Worse Recurrence-Free Survival in Patients with Primary Breast Cancer Receiving Adjuvant Tamoxifen Treatment. J Clin Med 7:N/A (2018). PubMed: 30154367
  • Park HJ  et al. Protein Phosphatase 2A and Its Methylation Modulating Enzymes LCMT-1 and PME-1 Are Dysregulated in Tauopathies of Progressive Supranuclear Palsy and Alzheimer Disease. J Neuropathol Exp Neurol 77:139-148 (2018). PubMed: 29281045
  • Garner EF  et al. FTY720 Decreases Tumorigenesis in Group 3 Medulloblastoma Patient-Derived Xenografts. Sci Rep 8:6913 (2018). PubMed: 29720672
  • Huang C  et al. Evidence of the impact of systemic inflammation on neuroinflammation from a non-bacterial endotoxin animal model. J Neuroinflammation 15:147 (2018). PubMed: 29776428
  • Kake S  et al. The role of SET/I2PP2A in canine mammary tumors. Sci Rep 7:4279 (2017). PubMed: 28655918
  • Dillinger B  et al. CD28 BlockadeEx VivoInduces Alloantigen-Specific Immune Tolerance but Preserves T-Cell Pathogen Reactivity. Front Immunol 8:1152 (2017). WB . PubMed: 28979262
  • Wang Y  et al. PP2A regulates SCF-induced cardiac stem cell migration through interaction with p38 MAPK. Life Sci 191:59-67 (2017). PubMed: 28986094
  • An XZ  et al. Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer. Oncotarget 7:24719-33 (2016). PubMed: 27034160
  • Yin Y  et al. Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling. Proc Natl Acad Sci U S A 113:E3773-81 (2016). PubMed: 27298345
  • Jeong AL  et al. Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway. Sci Rep 6:27391 (2016). PubMed: 27272709
  • Tsai YT  et al. Novel Cancer Therapeutics with Allosteric Modulation of the Mitochondrial C-Raf-DAPK Complex by Raf Inhibitor Combination Therapy. Cancer Res 75:3568-82 (2015). PubMed: 26100670
  • Inoue D  et al. SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS. Leukemia 29:847-57 (2015). PubMed: 25306901
  • Du TT  et al. GBA deficiency promotes SNCA/a-synuclein accumulation through autophagic inhibition by inactivated PPP2A. Autophagy 11:1803-20 (2015). PubMed: 26378614
  • Cristóbal I  et al. Phosphorylated protein phosphatase 2A determines poor outcome in patients with metastatic colorectal cancer. Br J Cancer 111:756-62 (2014). IHC . PubMed: 25003662
  • Nardi F  et al. Enhanced insulin sensitivity associated with provision of mono and polyunsaturated fatty acids in skeletal muscle cells involves counter modulation of PP2A. PLoS One 9:e92255 (2014). PubMed: 24632852
  • Cristóbal I  et al. PP2A inhibition is a common event in colorectal cancer and its restoration using FTY720 shows promising therapeutic potential. Mol Cancer Ther 13:938-47 (2014). Human . PubMed: 24448818
  • Borghgraef P  et al. Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice. PLoS One 8:e84442 (2013). WB ; Mouse . PubMed: 24376810
  • Sánchez I  et al. A novel function of Ataxin-1 in the modulation of PP2A activity is dysregulated in the spinocerebellar ataxia type 1. Hum Mol Genet 22:3425-37 (2013). PubMed: 23630944
  • Wang X  et al. Microcystin (-LR) induced testicular cell apoptosis via up-regulating apoptosis-related genes in vivo. Food Chem Toxicol 60:309-17 (2013). PubMed: 23891578
  • Khammanivong A  et al. S100A8/A9 (calprotectin) negatively regulates G2/M cell cycle progression and growth of squamous cell carcinoma. PLoS One 8:e69395 (2013). WB ; Human . PubMed: 23874958
  • Cao Z  et al. X-linked inhibitor of apoptosis protein (XIAP) regulation of cyclin D1 protein expression and cancer cell anchorage-independent growth via its E3 ligase-mediated protein phosphatase 2A/c-Jun axis. J Biol Chem 288:20238-47 (2013). WB ; Human . PubMed: 23720779
  • Oaks JJ  et al. Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies. Blood 122:1923-34 (2013). PubMed: 23926298
  • Lai CY  et al. Depletion of 4E-BP1 and regulation of autophagy lead to YXM110-induced anticancer effects. Carcinogenesis 34:2050-60 (2013). PubMed: 23633518
  • Liang D  et al. BAFF activates Erk1/2 promoting cell proliferation and survival by Ca(2+)-CaMKII-dependent inhibition of PP2A in normal and neoplastic B-lymphoid cells. Biochem Pharmacol N/A:N/A (2013). Human . PubMed: 24269630
  • DeGrande ST  et al. Molecular mechanisms underlying cardiac protein phosphatase 2A regulation in heart. J Biol Chem 288:1032-46 (2013). WB . PubMed: 23204520
  • Benziane B  et al. Activation of AMP-activated Protein Kinase Stimulates Na+,K+-ATPase Activity in Skeletal Muscle Cells. J Biol Chem 287:23451-63 (2012). WB . PubMed: 22610379
  • Ho YS  et al. Cigarette smoking accelerated brain aging and induced pre-Alzheimer-like neuropathology in rats. PLoS One 7:e36752 (2012). WB . PubMed: 22606286
  • Bertrand J  et al. Sex differences in the GSK3ß-mediated survival of adherent leukemic progenitors. Oncogene 31:694-705 (2012). Human . PubMed: 21725365
  • Barton-Pai A  et al. Tumor necrosis factor-a induces increased lung vascular permeability: a role for GSK3a/ß. Eur J Pharmacol 657:159-66 (2011). WB . PubMed: 21316358
  • Li T  et al. Microcystin-LR (MCLR) Induces a Compensation of PP2A Activity Mediated by a4 Protein in HEK293 Cells. Int J Biol Sci 7:740-52 (2011). WB ; Human . PubMed: 21698000
  • Kim KY  et al. Adiponectin-activated AMPK stimulates dephosphorylation of AKT through protein phosphatase 2A activation. Cancer Res 69:4018-26 (2009). WB ; Human . PubMed: 19366811

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