Overview

  • Product name

    Anti-PPCS antibody [EPR9453]
    See all PPCS primary antibodies
  • Description

    Rabbit monoclonal [EPR9453] to PPCS
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IPmore details
    Unsuitable for: Flow Cyt,ICC or IHC-P
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human PPCS aa 250-350 (C terminal). The exact sequence is proprietary.

  • Positive control

    • HeLa, 293T, SH-SY5Y and HepG2 whole cell lysate (ab7900).
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab140626 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 34 kDa.
IP 1/10 - 1/100.
  • Application notes
    Is unsuitable for Flow Cyt,ICC or IHC-P.
  • Target

    • Function

      Catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine.
    • Pathway

      Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 2/5.
    • Sequence similarities

      Belongs to the PPC synthetase family.
    • Information by UniProt
    • Database links

    • Alternative names

      • COAB antibody
      • FLJ11838 antibody
      • MGC117357 antibody
      • MGC138220 antibody
      • OTTHUMP00000008433 antibody
      • Phosphopantothenate--cysteine ligase antibody
      • Phosphopantothenoylcysteine synthetase antibody
      • PPC synthetase antibody
      • Ppcs antibody
      • PPCS_HUMAN antibody
      • RP11-163G10.1 antibody
      see all

    Images

    • All lanes : Anti-PPCS antibody [EPR9453] (ab140626) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : 293T cell lysate
      Lane 3 : SH-SY5Y cell lysate
      Lane 4 : HepG2 cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 34 kDa

    References

    This product has been referenced in:

    • Iuso A  et al. Mutations in PPCS, Encoding Phosphopantothenoylcysteine Synthetase, Cause Autosomal-Recessive Dilated Cardiomyopathy. Am J Hum Genet 102:1018-1030 (2018). Read more (PubMed: 29754768) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab140626.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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