Overview

  • Product name

    Anti-PPFIA4 antibody - N-terminal
    See all PPFIA4 primary antibodies
  • Description

    Rabbit polyclonal to PPFIA4 - N-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 173-222 of the Human PPFIA4 (NP_055868).

  • Positive control

    • WB: RPMI-822 cell lysate.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at -20ºC.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab136305 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 78 kDa.

Target

  • Function

    May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
  • Tissue specificity

    Expressed only in the heart, brain, and skeletal muscle.
  • Sequence similarities

    Belongs to the liprin family. Liprin-alpha subfamily.
    Contains 3 SAM (sterile alpha motif) domains.
  • Domain

    The N-terminal coiled coil regions mediate homodimerization preferentially and heterodimerization type alpha/alpha. The C-terminal, non-coiled coil regions mediate heterodimerization type alpha/beta and interaction with PTPRD, PTPRF and PTPRS.
  • Cellular localization

    Cytoplasm. Cell surface. Colocalizes with PTPRF at the cell surface.
  • Information by UniProt
  • Database links

  • Alternative names

    • KIAA0897 antibody
    • LIPA4_HUMAN antibody
    • Liprin alpha 4 antibody
    • Liprin-alpha-4 antibody
    • PPFIA 4 antibody
    • PPFIA4 antibody
    • Protein tyrosine phosphatase receptor type f polypeptide (PTPRF) interacting protein (liprin) alpha 4 antibody
    • Protein tyrosine phosphatase receptor type f polypeptide interacting protein alpha 4 antibody
    • Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4 antibody
    • PTPRF interacting protein alpha 4 antibody
    • PTPRF-interacting protein alpha-4 antibody
    see all

Images

  • Anti-PPFIA4 antibody - N-terminal (ab136305) at 1 µg/ml + RPMI-822 cell lysate at 10 µg

    Predicted band size: 78 kDa

References

ab136305 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab136305.
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