Overview

  • Product name

  • Description

    Rabbit polyclonal to PPIH
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Cow, Xenopus laevis, Zebrafish, Xenopus tropicalis
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-177 of Human PPIH (UniProt O43447).

  • Positive control

    • A549, HepG2 and HeLa whole cell lysates; HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab151246 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 19 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Function

    PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex. May act as a chaperone.
  • Sequence similarities

    Belongs to the cyclophilin-type PPIase family. PPIase H subfamily.
    Contains 1 PPIase cyclophilin-type domain.
  • Cellular localization

    Nucleus speckle. Cytoplasm. Colocalizes with spliceosomal snRNPs. A small proportion may also be cytoplasmic.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cyclophilin H antibody
    • CYP-20 antibody
    • CypH antibody
    • Peptidyl prolyl cis trans isomerase H antibody
    • Peptidyl-prolyl cis-trans isomerase H antibody
    • Peptidylprolyl isomerase H antibody
    • PPIase H antibody
    • PPIH antibody
    • PPIH_HUMAN antibody
    • RGD1564921 antibody
    • Rotamase H antibody
    • Small nuclear ribonucleoprotein particle specific cyclophilin H antibody
    • Small nuclear ribonucleoprotein particle-specific cyclophilin H antibody
    • SnuCyp 20 antibody
    • U snRNP associated cyclophilin SnuCyp 20 antibody
    • U-snRNP-associated cyclophilin SnuCyp-20 antibody
    • USA CYP antibody
    • USA-CYP antibody
    • USACYP antibody
    see all

Images

  • Anti-PPIH antibody (ab151246) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size: 19 kDa



    12% SDS PAGE
  • Immunofluorescent analysis of paraformaldehyde-fixed HeLa cells labeling PPIH with ab151246 at 1/200 dilution. Lower image shows cells co-stained with Hoechst 33342.

References

ab151246 has not yet been referenced specifically in any publications.

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