• Product name
  • Description
    Rabbit polyclonal to PPIP5K2
  • Host species
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 612-661 (LSSCQQRVKA RLHEILQKDR DFTAEDYEKL TPSGSISLIK SMHLIKNPVK) of human HISPPD1 (NP_056031).

  • Positive control
    • Transfected 293T cell lysate



Our Abpromise guarantee covers the use of ab87054 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 138 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • Function
    Bifunctional inositol kinase that catalyzes the formation of diphosphoinositol pentakisphosphate (InsP7 or PP-InsP5) and bi-diphosphoinositol tetrakisphosphate (InsP8 or PP2-InsP4). Converts inositolitol hexakisphosphate (InsP6) to InsP7. Also able to convert InsP7 to InsP8. Probably specifically mediates the formation of 4PP-InsP5 and 6PP-InsP5 InsP7 isomers but not of 5PP-IP5 InsP7 isomer.
  • Sequence similarities
    Belongs to the histidine acid phosphatase family. VIP1 subfamily.
  • Cellular localization
    Cytoplasm > cytosol.
  • Information by UniProt
  • Database links
  • Alternative names
    • Diphosphoinositol pentakisphosphate kinase 2 antibody
    • HISPPD1 antibody
    • Histidine acid phosphatase domain containing 1 antibody
    • Histidine acid phosphatase domain containing protein 1 antibody
    • Histidine acid phosphatase domain-containing protein 1 antibody
    • hsVIP2 antibody
    • Inositol heptaphosphate kinase 2 antibody
    • Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 antibody
    • InsP6 and PP IP5 kinase 2 antibody
    • InsP6 and PP-IP5 kinase 2 antibody
    • IP7K2 antibody
    • PP IP5 kinase 2 antibody
    • Ppip5k2 antibody
    • VIP1 homolog 2 antibody
    • VIP2 antibody
    • VIP2_HUMAN antibody
    see all


  • Anti-PPIP5K2 antibody (ab87054) at 1 µg/ml + transfected 293T cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size: 138 kDa

    Gel concentration: 6-18%


This product has been referenced in:
  • Yousaf R  et al. Mutations in Diphosphoinositol-Pentakisphosphate Kinase PPIP5K2 are associated with hearing loss in human and mouse. PLoS Genet 14:e1007297 (2018). Read more (PubMed: 29590114) »

See 1 Publication for this product

Customer reviews and Q&As

Flow Cytometry
Human Cell (HEK293 transfected with PPIP5K2 construct)
HEK293 transfected with PPIP5K2 construct
70% ethanol
Yes - Triton-X
Gating Strategy
Alexa Fluor 488 positive cells

Abcam user community

Verified customer

Submitted Dec 03 2012

Thank you for your reply.

Yes, I have made a note that the code will be redeemed for FACS instead of IF. Please let me know if you have any questions. I wish you the best of luck with your experiments.

Have a great day!

I am very pleased to hear you would like to accept our offer and test ab87054 in IF. This code will give you: 1 free primary antibody before the expiration date. To redeem this offer, please submit an Abreview forIF and include this code in the Additio...

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Yes, you have 4 months to purchase the antibody, test it, submit the review, and redeem the code. The code expires 4 months from the date of issue, regardless of when the review is submitted.

I hope this clarifies things.Please do not h...

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Thank you for your reply.

Yes, as long as the discount code is referenced when trying to redeem it later on you can receive the free antibody.

I hope this information is helpful. Please do not hesitate to contact me if y...

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Thank you very much for your interest in ab87054.

To our knowledge, ab87054 has not been tested in IF. Therefore, I can offer a discount off a future purchase if you buy ab87054 now, test it inIF and submit feedback to us in the form of an A...

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Thank you for contacting us. Because we carry over 70,000 products, it isn't feasible for us to keep small sample sizes of our products.

We are happy to reassure our customers that all of our products are covered by our Abpromise, which guar...

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