Overview

  • Product name

  • Description

    Rabbit polyclonal to PPP2R5B
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Cow
  • Immunogen

    Recombinant fragment within Human PPP2R5B (internal sequence). The exact sequence is proprietary.
    Database link: Q15173

  • Positive control

    • WB: A431 whole cell extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab227476 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 57 kDa.

Target

  • Function

    The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues.
  • Tissue specificity

    Highest expression in brain.
  • Sequence similarities

    Belongs to the phosphatase 2A regulatory subunit B56 family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • 2A5B_HUMAN antibody
    • B56B antibody
    • Beta isoform of regulatory subunit B56 protein phosphatase 2A antibody
    • FLJ35411 antibody
    • PP2A B subunit B' beta isoform antibody
    • PP2A B subunit B56 beta isoform antibody
    • PP2A B subunit isoform B' beta antibody
    • PP2A B subunit isoform B''-beta antibody
    • PP2A B subunit isoform B56-beta antibody
    • PP2A B subunit isoform PR61-beta antibody
    • PP2A B subunit isoform R5-beta antibody
    • PP2A B subunit PR61 beta isoform antibody
    • PP2A B subunit R5 beta isoform antibody
    • PPP2R5B antibody
    • PR 61B antibody
    • PR61B antibody
    • Protein phosphatase 2 regulatory subunit B (B56) beta antibody
    • Protein phosphatase 2 regulatory subunit B (B56) beta isoform antibody
    • Protein phosphatase 2 regulatory subunit B' beta antibody
    • Protein phosphatase 2 regulatory subunit B' beta isoform antibody
    • Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit beta isoform antibody
    • Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform antibody
    see all

Images

  • Anti-PPP2R5B antibody (ab227476) at 1/1000 dilution + A431 (human epidermoid carcinoma cell line) whole cell extract at 30 µg

    Predicted band size: 57 kDa



    7.5% SDS-PAGE gel.

References

ab227476 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab227476.
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