Anti-PPP2R5B antibody (ab97295)

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Overview

  • Product name

    Anti-PPP2R5B antibody
    See all PPP2R5B primary antibodies

  • Description

    Rabbit polyclonal to PPP2R5B

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Synthetic peptide within Human PPP2R5B aa 434-497. The exact sequence is proprietary.

  • Positive control

    • A431 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab97295 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 57 kDa.

Target

  • Function

    The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues.

  • Tissue specificity

    Highest expression in brain.

  • Sequence similarities

    Belongs to the phosphatase 2A regulatory subunit B56 family.

  • Cellular localization

    Cytoplasm.
  • Information by UniProt

  • Database links

    • Alternative names

      • 2A5B_HUMAN antibody
      • B56B antibody
      • Beta isoform of regulatory subunit B56 protein phosphatase 2A antibody
      • FLJ35411 antibody
      • PP2A B subunit B' beta isoform antibody
      • PP2A B subunit B56 beta isoform antibody
      • PP2A B subunit isoform B' beta antibody
      • PP2A B subunit isoform B''-beta antibody
      • PP2A B subunit isoform B56-beta antibody
      • PP2A B subunit isoform PR61-beta antibody
      • PP2A B subunit isoform R5-beta antibody
      • PP2A B subunit PR61 beta isoform antibody
      • PP2A B subunit R5 beta isoform antibody
      • PPP2R5B antibody
      • PR 61B antibody
      • PR61B antibody
      • Protein phosphatase 2 regulatory subunit B (B56) beta antibody
      • Protein phosphatase 2 regulatory subunit B (B56) beta isoform antibody
      • Protein phosphatase 2 regulatory subunit B' beta antibody
      • Protein phosphatase 2 regulatory subunit B' beta isoform antibody
      • Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit beta isoform antibody
      • Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform antibody
      see all

    Images

    • Western blot - Anti-PPP2R5B antibody (ab97295)
      Western blot - Anti-PPP2R5B antibody (ab97295)
      Anti-PPP2R5B antibody (ab97295) at 1/1000 dilution + A431 whole cell lysate at 30 µg

      Predicted band size: 57 kDa



      7.5% SDS PAGE

    References

    ab97295 has not yet been referenced specifically in any publications.

    Publishing research using ab97295? Please let us know so that we can cite the reference in this datasheet.

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