Overview

  • Product name
    Anti-PPP2R5B antibody
    See all PPP2R5B primary antibodies
  • Description
    Rabbit polyclonal to PPP2R5B
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human PPP2R5B aa 434-497. The exact sequence is proprietary.

  • Positive control
    • A431 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab97295 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 57 kDa.

Target

  • Function
    The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues.
  • Tissue specificity
    Highest expression in brain.
  • Sequence similarities
    Belongs to the phosphatase 2A regulatory subunit B56 family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
    • Alternative names
      • 2A5B_HUMAN antibody
      • B56B antibody
      • Beta isoform of regulatory subunit B56 protein phosphatase 2A antibody
      • FLJ35411 antibody
      • PP2A B subunit B' beta isoform antibody
      • PP2A B subunit B56 beta isoform antibody
      • PP2A B subunit isoform B' beta antibody
      • PP2A B subunit isoform B''-beta antibody
      • PP2A B subunit isoform B56-beta antibody
      • PP2A B subunit isoform PR61-beta antibody
      • PP2A B subunit isoform R5-beta antibody
      • PP2A B subunit PR61 beta isoform antibody
      • PP2A B subunit R5 beta isoform antibody
      • PPP2R5B antibody
      • PR 61B antibody
      • PR61B antibody
      • Protein phosphatase 2 regulatory subunit B (B56) beta antibody
      • Protein phosphatase 2 regulatory subunit B (B56) beta isoform antibody
      • Protein phosphatase 2 regulatory subunit B' beta antibody
      • Protein phosphatase 2 regulatory subunit B' beta isoform antibody
      • Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit beta isoform antibody
      • Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform antibody
      see all

    Images

    • Western blot - Anti-PPP2R5B antibody (ab97295)
      Western blot - Anti-PPP2R5B antibody (ab97295)
      Anti-PPP2R5B antibody (ab97295) at 1/1000 dilution + A431 whole cell lysate at 30 µg

      Predicted band size: 57 kDa



      7.5% SDS PAGE

    References

    ab97295 has not yet been referenced specifically in any publications.

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