Recombinant
RabMAb

Recombinant Anti-PPP6C/Ppv antibody [EPR8764] - BSA and Azide free (ab248413)

Overview

  • Product name

    Anti-PPP6C/Ppv antibody [EPR8764] - BSA and Azide free
    See all PPP6C/Ppv primary antibodies
  • Description

    Rabbit monoclonal [EPR8764] to PPP6C/Ppv - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, WB, IP, Flow Cytmore details
    Unsuitable for: IHC-P
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human PPP6C/Ppv aa 250-350 (C terminal). The exact sequence is proprietary.
    Database link: O00743

  • General notes

    ab248413 is a PBS-only buffer format of ab131335. Please refer to ab131335 for recommended dilutions, protocols, and image data.

     

     This product was previously labelled as PPP6C

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Dissociation constant (KD)

    KD = 5.00 x 10 -11 M
    Learn more about KD
  • Concentration information loading...
  • Purity

    Affinity purified
  • Clonality

    Monoclonal
  • Clone number

    EPR8764
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab248413 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 35 kDa.
IP Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration.
  • Application notes
    Is unsuitable for IHC-P.
  • Target

    • Function

      Catalytic subunit of protein phospatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7.
    • Tissue specificity

      Ubiquitously expressed in all tissues tested with highest expression levels in testis, heart, kidney, brain, stomach, liver and skeletal muscle and lowest in placenta, lung colon and spleen.
    • Sequence similarities

      Belongs to the PPP phosphatase family. PP-6 (PP-V) subfamily.
    • Cellular localization

      Cytoplasm.
    • Information by UniProt
    • Database links

    • Alternative names

      • FLJ92648 antibody
      • MGC12249 antibody
      • PP 6 antibody
      • PP6 antibody
      • PP6C antibody
      • PPP 6 antibody
      • PPP 6C antibody
      • PPP6 antibody
      • PPP6_HUMAN antibody
      • Ppp6c antibody
      • Protein phosphatase 6 catalytic subunit antibody
      • Serine/threonine protein phosphatase 6 antibody
      • Serine/threonine protein phosphatase catalytic subunit antibody
      • Serine/threonine-protein phosphatase 6 catalytic subunit antibody
      see all

    References

    ab248413 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab248413.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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