Overview

  • Product name

    Anti-PR3 antibody [EPR6277]
    See all PR3 primary antibodies
  • Description

    Rabbit monoclonal [EPR6277] to PR3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
    Unsuitable for: Flow Cyt,ICC or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    A synthetic peptide corresponding to residues in Human PR3 (UniProt ID: P24158).

  • Positive control

    • HL60 and Human spleen lysates; Human kidney tissue
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab133613 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 29 kDa (predicted molecular weight: 27 kDa).
IHC-P 1/100 - 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
  • Application notes
    Is unsuitable for Flow Cyt,ICC or IP.
  • Target

    • Function

      Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
    • Sequence similarities

      Belongs to the peptidase S1 family. Elastase subfamily.
      Contains 1 peptidase S1 domain.
    • Information by UniProt
    • Database links

    • Alternative names

      • ACPA antibody
      • AGP 7 antibody
      • AGP7 antibody
      • AGP7 serine proteinase antibody
      • Azurophil Granule Protein 7 antibody
      • C ANCA antibody
      • C ANCA antigen antibody
      • C-ANCA antigen antibody
      • CANCA antibody
      • EC 3.4.21.76 antibody
      • Leukocyte proteinase 3 antibody
      • MBN antibody
      • MBT antibody
      • MBT WEGENER AUTOANTIGEN antibody
      • Myeloblastin antibody
      • Neutrophil proteinase 4 antibody
      • NP 4 antibody
      • NP-4 antibody
      • NP4 antibody
      • P29 antibody
      • PR 3 antibody
      • PR-3 antibody
      • PR3 antibody
      • Proteinase 3 antibody
      • Proteinase3 antibody
      • PRTN 3 antibody
      • Prtn3 antibody
      • PRTN3_HUMAN antibody
      • Serine proteinase neutrophil Wegener granulomatosis autoantigen antibody
      • Serine proteinase, neutrophil antibody
      • Wegener autoantigen antibody
      • Wegener granulomatosis autoantigen antibody
      see all

    Images

    • All lanes : Anti-PR3 antibody [EPR6277] (ab133613) at 1/1000 dilution

      Lane 1 : HL60 lysates
      Lane 2 : Human spleen lysates

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 27 kDa

    • Immunohistochemical analysis of PR3 in paraffin embedded Human kidney tissue labelled with ab133613 at a 1/100 dilution.
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    ab133613 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab133613.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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