Overview

  • Product name

    Anti-PRAX-1 antibody
  • Description

    Rabbit polyclonal to PRAX-1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    antigen sequence: RTASTSTLGE KDPGPAAPSL AKQEAEWTAG EACPASSSTQ GARAQQAPNT EMCQGGDPGS GLRPRAEKED TAELGVHLVN SLVDHGRNSD LSD, corresponding to internal sequence amino acids 1167-1259 of Human PRAX-1.

  • Positive control

    • Human esophagus tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab121856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Tissue specificity

    Predominantly expressed in brain, pituitary gland and thymus in adults. In adult brain, highest expression found in temporal lobe and the putamen, followed by amygdala, caudate nucleus, cerebral cortex, occipital and frontal lobe. A high expression level is also observed in fetal tissues like brain, heart, kidney and thymus.
  • Sequence similarities

    Belongs to the RIMBP family.
    Contains 3 fibronectin type-III domains.
    Contains 3 SH3 domains.
  • Domain

    The SH3 and proline-rich domain is required for the interaction with BZRP and the second SH3 domain mediates binding to a proline-rich motif in RIMS1 and RIMS2.
  • Cellular localization

    Cytoplasm. Mitochondrion. Preferentially expressed in the mitochondria in the presence of BZRP.
  • Information by UniProt
  • Database links

  • Alternative names

    • Bzrap1 antibody
    • D230016K05 antibody
    • mKIAA0612 antibody
    • PBR-IP antibody
    • Peripheral benzodiazepine receptor-interacting protein antibody
    • Peripheral-type benzodiazepine receptor-associated protein 1 antibody
    • PRAX 1 antibody
    • PRAX-1 antibody
    • RBP1 antibody
    • RIM binding protein 1 antibody
    • RIM-BP1 antibody
    • RIMB1_HUMAN antibody
    • RIMBP1 antibody
    • RIMS-binding protein 1 antibody
    • RP23-449P23.4 antibody
    see all

Images

  • ab121856, at 1/40 dilution, staining PRAX-1 in squamous epithelial cells of paraffin-embedded Human esophagus by Immunohistochemistry.

References

ab121856 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab121856.
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