Key features and details
- Rabbit polyclonal to PRAX-1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-PRAX-1 antibody
DescriptionRabbit polyclonal to PRAX-1
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
- Human esophagus tissue.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab121856 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
Tissue specificityPredominantly expressed in brain, pituitary gland and thymus in adults. In adult brain, highest expression found in temporal lobe and the putamen, followed by amygdala, caudate nucleus, cerebral cortex, occipital and frontal lobe. A high expression level is also observed in fetal tissues like brain, heart, kidney and thymus.
Sequence similaritiesBelongs to the RIMBP family.
Contains 3 fibronectin type-III domains.
Contains 3 SH3 domains.
DomainThe SH3 and proline-rich domain is required for the interaction with BZRP and the second SH3 domain mediates binding to a proline-rich motif in RIMS1 and RIMS2.
Cellular localizationCytoplasm. Mitochondrion. Preferentially expressed in the mitochondria in the presence of BZRP.
- Information by UniProt
- Bzrap1 antibody
- D230016K05 antibody
- mKIAA0612 antibody
ab121856 has been referenced in 1 publication.
- Liu D et al. microRNA-155 Modulates Hepatic Stellate Cell Proliferation, Apoptosis, and Cell Cycle Progression in Rats With Alcoholic Hepatitis via the MAPK Signaling Pathway Through Targeting SOCS1. Front Pharmacol 11:270 (2020). PubMed: 32317960