Key features and details
- Peripheral α adrenoceptor antagonist. Melatonin antagonist.
- CAS Number: 19237-84-4
- Purity: > 99%
- Soluble in DMSO to 25 mM and in ethanol to 5 mM
- Form / State: Solid
- Source: Synthetic
Product namePrazosin hydrochloride, Peripheral alpha adrenoceptor antagonist
DescriptionPeripheral α adrenoceptor antagonist. Melatonin antagonist.
Peripheral α1 and α2 adrenoceptor antagonist. Orally active vasodilator. Also melatonin MT3 antagonist.
Chemical name[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanylmethanone hydrochloride
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 25 mM and in ethanol to 5 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120238 has been referenced in 2 publications.
- Tyurin-Kuzmin PA et al. Activation of ß-adrenergic receptors is required for elevated a1A-adrenoreceptors expression and signaling in mesenchymal stromal cells. Sci Rep 6:32835 (2016). PubMed: 27596381
- Meitzen J et al. ß1-Adrenergic receptors activate two distinct signaling pathways in striatal neurons. J Neurochem 116:984-95 (2011). PubMed: 21143600