• Product name

  • Description

    Rabbit polyclonal to PRD
  • Host species

  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: IP
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Giant Panda
  • Immunogen

    Synthetic peptide within Human PRD aa 443-493. The exact sequence is proprietary.
    Database link: P12955

  • Positive control

    • WB: HeLa, HEK-293T and Jurkat whole cell lysates.
  • General notes

     This product was previously labelled as PEPD




Our Abpromise guarantee covers the use of ab226414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Predicted molecular weight: 55 kDa.
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function

      Splits dipeptides with a prolyl or hydroxyprolyl residue in the C-terminal position. Plays an important role in collagen metabolism because the high level of iminoacids in collagen.
    • Involvement in disease

      Defects in PEPD are a cause of prolidase deficiency (PD) [MIM:170100]. Prolidase deficiency is an autosomal recessive disorder associated with iminodipeptiduria. The clinical phenotype includes skin ulcers, mental retardation, recurrent infections, and a characteristic facies. These features, however are incompletely penetrant and highly variable in both age of onset and severity. There is a tight linkage between the polymorphisms of prolidase and the myotonic dystrophy trait.
    • Sequence similarities

      Belongs to the peptidase M24B family. Eukaryotic-type prolidase subfamily.
    • Information by UniProt
    • Database links

    • Alternative names

      • Aminoacyl L proline hydrolase antibody
      • Imidodipeptidase antibody
      • MGC10905 antibody
      • MGC95081 antibody
      • Pep 4 antibody
      • Pep4 antibody
      • pepD antibody
      • PEPD_HUMAN antibody
      • Peptidase 4 antibody
      • Peptidase D antibody
      • Prolidase antibody
      • Proline dipeptidase antibody
      • X pro dipeptidase antibody
      • X-Pro dipeptidase antibody
      • Xaa-Pro dipeptidase antibody
      see all


    • All lanes : Anti-PRD antibody (ab226414) at 0.1 µg/ml

      Lane 1 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
      Lane 2 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate
      Lane 3 : Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate

      Lysates/proteins at 50 µg per lane.

      Developed using the ECL technique.

      Predicted band size: 55 kDa

      Exposure time: 3 minutes

      Cell lysates were prepared using NETN lysis buffer.


    ab226414 has not yet been referenced specifically in any publications.

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