Anti-PRDC antibody - C-terminal (ab228736)
Key features and details
- Rabbit polyclonal to PRDC - C-terminal
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-PRDC antibody - C-terminal
See all PRDC primary antibodies -
Description
Rabbit polyclonal to PRDC - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Rhesus monkey
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Immunogen
Synthetic peptide within Human PRDC (C terminal). The exact sequence is proprietary. Carrier-protein conjugated.
Database link: Q9H772 -
Positive control
- WB: A549 and IMR32 whole cell extracts. IHC-P: Human placenta tissue.
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General notes
This product was previously labelled as GREM2
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab228736 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 19 kDa. | |
| IHC-P | 1/100 - 1/1000. |
Target
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Function
Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner. Antagonized BMP4-induced suppression of progesterone production in granulosa cells. -
Sequence similarities
Belongs to the DAN family.
Contains 1 CTCK (C-terminal cystine knot-like) domain. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 64388 Human
- Entrez Gene: 23893 Mouse
- Entrez Gene: 289264 Rat
- Entrez Gene: 708280 Rhesus monkey
- Omim: 608832 Human
- SwissProt: Q9H772 Human
- SwissProt: O88273 Mouse
- Unigene: 98206 Human
see all -
Alternative names
- BMP antagonist 2 antibody
- CKTSF1B2 antibody
- Cysteine knot superfamily 1 antibody
see all
Images
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Western blot - Anti-PRDC antibody - C-terminal (ab228736)Anti-PRDC antibody - C-terminal (ab228736) at 1/500 dilution + A549 (human lung carcinoma cell line) whole cell extract at 30 µg
Predicted band size: 19 kDa15% SDS-PAGE gel.
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Western blot - Anti-PRDC antibody - C-terminal (ab228736)Anti-PRDC antibody - C-terminal (ab228736) at 1/500 dilution + IMR32 whole cell extract at 30 µg
Predicted band size: 19 kDa15% SDS-PAGE gel.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PRDC antibody - C-terminal (ab228736)Paraffin-embedded human placenta tissue stained for PRDC using ab228736 at 1/100 dilution in immunohistochemical analysis.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab228736 has not yet been referenced specifically in any publications.
