Anti-PRDC antibody - C-terminal (ab228736)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-PRDC antibody - C-terminal
See all PRDC primary antibodies -
Description
Rabbit polyclonal to PRDC - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Rhesus monkey
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Immunogen
Synthetic peptide within Human PRDC (C terminal). The exact sequence is proprietary. Carrier-protein conjugated.
Database link: Q9H772 -
Positive control
- WB: A549 and IMR32 whole cell extracts. IHC-P: Human placenta tissue.
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General notes
This product was previously labelled as GREM2
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab228736 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 19 kDa. | |
| IHC-P | 1/100 - 1/1000. |
Target
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Function
Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner. Antagonized BMP4-induced suppression of progesterone production in granulosa cells. -
Sequence similarities
Belongs to the DAN family.
Contains 1 CTCK (C-terminal cystine knot-like) domain. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 64388 Human
- Entrez Gene: 23893 Mouse
- Entrez Gene: 289264 Rat
- Entrez Gene: 708280 Rhesus monkey
- Omim: 608832 Human
- SwissProt: Q9H772 Human
- SwissProt: O88273 Mouse
- Unigene: 98206 Human
see all -
Alternative names
- BMP antagonist 2 antibody
- CKTSF1B2 antibody
- Cysteine knot superfamily 1 antibody
see all
Images
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Western blot - Anti-PRDC antibody - C-terminal (ab228736)Anti-PRDC antibody - C-terminal (ab228736) at 1/500 dilution + A549 (human lung carcinoma cell line) whole cell extract at 30 µg
Predicted band size: 19 kDa15% SDS-PAGE gel.
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Western blot - Anti-PRDC antibody - C-terminal (ab228736)Anti-PRDC antibody - C-terminal (ab228736) at 1/500 dilution + IMR32 whole cell extract at 30 µg
Predicted band size: 19 kDa15% SDS-PAGE gel.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PRDC antibody - C-terminal (ab228736)Paraffin-embedded human placenta tissue stained for PRDC using ab228736 at 1/100 dilution in immunohistochemical analysis.
References
ab228736 has not yet been referenced specifically in any publications.
