Key features and details
- Glucocorticoid. Anti-inflammatory and potent immunosuppressive agent.
- CAS Number: 50-24-8
- Purity: > 98%
- Form / State: Solid
- Source: Synthetic
Product namePrednisolone (Predonine), glucocorticoid
DescriptionGlucocorticoid. Anti-inflammatory and potent immunosuppressive agent.
Biological descriptionGlucocorticoid (Ki = 4 nM). Anti-inflammatory and immunosuppressive agent. Recruits TIF-2 (EC50 = 3 nM). Upregulates cdk inhibitors Plk3, Bcl-xl and p53. Shows antitumor effects in vivo. Orally active.
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Molecular processes
- Mitochondrial transcription
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142455 has not yet been referenced specifically in any publications.