Overview

  • Product name

    Prednisolone (Predonine), glucocorticoid
  • Description

    Glucocorticoid. Anti-inflammatory and potent immunosuppressive agent.
  • Biological description

    Glucocorticoid (Ki = 4 nM). Anti-inflammatory and immunosuppressive agent. Recruits TIF-2 (EC50 = 3 nM). Upregulates cdk inhibitors Plk3, Bcl-xl and p53. Shows antitumor effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    50-24-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • van Lierop MJ  et al. Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index. PLoS One 7:e48385 (2012). Read more (PubMed: 23152771) »
  • Frijters R  et al. Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor. BMC Genomics 11:359 (2010). Read more (PubMed: 20525385) »
  • Taylor F  et al. Chlorambucil and prednisolone chemotherapy for dogs with inoperable mast cell tumours: 21 cases. J Small Anim Pract 50:284-9 (2009). Read more (PubMed: 19527421) »

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