Key features and details
- Rabbit polyclonal to PRG2
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-PRG2 antibody
See all PRG2 primary antibodies
DescriptionRabbit polyclonal to PRG2
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Recombinant fragment corresponding to a region within amino acids 1-222 of Human PRG2.
- Jurkat, K562, THP-1 and HL-60 whole cell lysates; Human hepatoma tissue.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab154655 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 25 kDa.|
|IHC-P||1/100 - 1/1000.|
FunctionCytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.
Tissue specificityHigh levels of the proform in placenta and pregnancy serum; in placenta, localized to X cells of septa and anchoring villi. Lower levels in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow and colon.
Sequence similaritiesContains 1 C-type lectin domain.
Developmental stageLevels of the proform increase in serum and placenta during pregnancy.
Cellular localizationCytoplasmic vesicle > secretory vesicle. The proform is secreted. The mature protein is found in the matrix of the eosinophil's large specific granule and Secreted. The proform is secreted.
- Information by UniProt
- BMPG antibody
- EMBP antibody
- Eosinophil granule major basic protein antibody
All lanes : Anti-PRG2 antibody (ab154655) at 1/1000 dilution
Lane 1 : Jurkat whole cell lysate
Lane 2 : K562 whole cell lysate
Lane 3 : THP-1 whole cell lysate
Lane 4 : HL-60 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 25 kDa
12% SDS PAGE
Immunohistochemical analysis of paraffin-embedded Human hepatoma tissue labeling PRG2 with ab154655 at 1/500 dilution.
ab154655 has not yet been referenced specifically in any publications.