Overview

  • Product name

    PRIMA-1MET, p53 activity
  • Description

    Restores mutant p53 activity
  • Alternative names

    • 2-(Hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one
    • 2-(hydroxymethyl)-2-(methoxymethyl)quinuclidin-3-one
    • APR-246
    • PRIMA-1(MET)
  • Purity

    > 98%
  • CAS Number

    5291-32-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-(Hydroxymethyl)-2-(methoxymethyl)quinuclidin-3-one
  • Molecular weight

    199.25
  • Molecular formula

    C10H17NO3
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water and in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

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