Low endotoxin, azide-free bioactive antibodies

​​Antibodies for in vitro and in vivo studies, including neutralization, blocking or activation/proliferation.

​​​​The presence of endotoxin can significantly impact both in vitro and in vivo experiments, causing non specific cellular responses and false readings in cell-based assays. 

Endotoxin is an aggregate of acidic lipopolysaccharides (LPS) that is shed from bacteria and is a heat-stable ubiquitous contaminant. Although bacteria are often removed by using a 0.2 μm sterilizing grade filter, LPS contamination is difficult to eliminate via filtering or autoclaving. Limulus amoebocyte lysate (LAL) assays are the most commonly used endotoxin detection methods. 

Explore our range of Low Endotoxin, Azide Free antibodies:

  • Endotoxin levels ≤ 1 EU/ml  as determined by the LAL assay
  • Azide-free and carrier-free
  • Supplied at 1 mg/mL concentration
  • Quality tested in a range of applications, including flow cytometry and functional activity assays
  • Bulk sizes and custom concentration available -> Contact our sales team​ 


SELECTED REFERENCES

​HLA Class I (ab80080​)

  • Wu H  et al. IFN-t Mediated Control of Bovine Major Histocompatibility Complex Class I Expression and Functionviathe Regulation of bta-miR-148b/152 in Bovine Endometrial Epithelial Cells. Front Immunol 9:167 (2018) PubMed ID: 29456541

CD36 (ab80080​)

  • Thackeray JT  et al. Insulin supplementation attenuates cancer-induced cardiomyopathy and slows tumor disease progression. JCI Insight 2:N/A (2017) PubMed ID: 28515362

Rabbit IgG - Isotype Contr​ol (ab199376)

  • Theret L  et al. Identification of LRP-1 as an endocytosis and recycling receptor for ß1-integrin in thyroid cancer cells. Oncotarget 8:78614-78632 (2017) PubMed ID: 2910825

HLA-DR (ab215985)

  • Ludwig RJ et al. Activated, not resting, platelets increase leukocyte rolling in murine skin utilizing a distinct set of adhesion molecules. J Invest Dermatol 122:830-6 (2004) PubMed ID: 25744981  



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