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Antibodies for in vitro and in vivo studies, including neutralization, blocking or activation/proliferation.
The presence of endotoxin can significantly impact both in vitro and in vivo experiments, causing non specific cellular responses and false readings in cell-based assays.
Endotoxin is an aggregate of acidic lipopolysaccharides (LPS) that is shed from bacteria and is a heat-stable ubiquitous contaminant. Although bacteria are often removed by using a 0.2 μm sterilizing grade filter, LPS contamination is difficult to eliminate via filtering or autoclaving. Limulus amoebocyte lysate (LAL) assays are the most commonly used endotoxin detection methods.
Explore our range of Low Endotoxin, Azide Free antibodies:
HLA Class I (ab80080)
Rabbit IgG - Isotype Control (ab199376)