Key features and details
- Rabbit polyclonal to Prion protease resistant protein 27-30
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Prion protease resistant protein 27-30 antibody
See all Prion protease resistant protein 27-30 primary antibodies
DescriptionRabbit polyclonal to Prion protease resistant protein 27-30
SpecificityRecognizes PrPC, with the potential fo PrPSC detection.
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Sheep, Cow
Synthetic peptide corresponding to Human Prion protease resistant protein 27-30. Peptide derived from the C-terminus of third a-helical domain of human prion protein.
Database link: P04156
- IHC-P: Human brain (cortex) tissue.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 8.00
Preservative: 0.05% Sodium azide
Constituents: 0.32% Tris HCl, 1% BSA
Concentration information loading...
Our Abpromise guarantee covers the use of ab230340 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
For immunohistochemistry on paraffin-embedded tissues, a buffer, pH6.0 is suggeted for antigen retrieval.
RelevanceThe protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein.
Cellular localizationCell Membrane; lipid-anchor; GPI-anchor
- ASCR antibody
- CD230 antibody
- CD230 antigen antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab230340 has not yet been referenced specifically in any publications.