Key features and details
- Sheep polyclonal to proANP
- Suitable for: ELISA, RIA
- Reacts with: Human
- Isotype: IgG
Product nameAnti-proANP antibody
See all proANP primary antibodies
DescriptionSheep polyclonal to proANP
SpecificitySynthetic human proANP (aa 31-67). There were no cross reactivities obtained with human proANP (aa 67-98) and human proANP (aa 1-30).
Tested applicationsSuitable for: ELISA, RIAmore details
Species reactivityReacts with: Human
Predicted to work with: Rabbit, Cat, Dog, Chimpanzee, Gorilla
- Recombinant Human Natriuretic peptides A protein (ab114317) can be used as a positive control in WB.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferConstituent: Whole serum
Concentration information loading...
Our Abpromise guarantee covers the use of ab14349 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent dilution.|
FunctionHormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Involvement in diseaseAtrial standstill 2
Atrial fibrillation, familial, 6
Sequence similaritiesBelongs to the natriuretic peptide family.
modificationsCleaved by CORIN upon secretion to produce the functional hormone.
Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity.
- Information by UniProt
- ANF antibody
- ANF_HUMAN antibody
- ANP antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab14349 has not yet been referenced specifically in any publications.