Product nameAnti-Proapoptotic Caspase Adaptor Protein antibody [EPR11543(B)]
See all Proapoptotic Caspase Adaptor Protein primary antibodies
DescriptionRabbit monoclonal [EPR11543(B)] to Proapoptotic Caspase Adaptor Protein
Tested applicationsSuitable for: WB, IPmore details
Unsuitable for: Flow Cyt,ICC or IHC
Species reactivityReacts with: Human
Does not react with: Mouse, Rat
Synthetic peptide within Human Proapoptotic Caspase Adaptor Protein (Cysteine residue). The exact sequence is proprietary.
Database link: Q8WU39
- Daudi, Ramos and Raji cell lysates.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents
This product is a recombinant rabbit monoclonal antibody.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab170891 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/10000 - 1/50000. Predicted molecular weight: 21 kDa.|
|IP||1/10 - 1/100.|
RelevanceProapoptotic Caspase Adaptor Protein associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity By similarity. Isoform 2 may be involved in regulation of apoptosis.
Cellular localizationIsoform 1: Endoplasmic reticulum Isoform 2: Cytoplasm. Note: Diffuse granular localization in the cytoplasm surrounding the nucleus.
- MZB1 antibody
- Caspase 2 binding protein antibody
- FLJ32987 antibody
Western blot analysis on immunoprecipitation pellet from (1) Raji cell lysate or (2) 1X PBS (negative control) immunoprecipitated using ab170891 at 1/10 dilution. Detection utilized HRP-conjugated anti-rabbit IgG which preferentially detects the non-reduced form of rabbit IgG.
All lanes : Anti-Proapoptotic Caspase Adaptor Protein antibody [EPR11543(B)] (ab170891) at 1/10000 dilution
Lane 1 : Daudi cell lysates
Lane 2 : Ramos cell lysates
Lane 3 : Raji cell lysates
Lysates/proteins at 10 µg per lane.
All lanes : Goat anti-rabbit HRP at 1/2000 dilution
Predicted band size: 21 kDa
ab170891 has not yet been referenced specifically in any publications.