Anti-ProBMP2 antibody (ab230498)
Key features and details
- Rabbit polyclonal to ProBMP2
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ProBMP2 antibody -
Description
Rabbit polyclonal to ProBMP2 -
Host species
Rabbit -
Specificity
ab230498 recognizes endogenous levels of BMP2 protein. -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Sheep, Rabbit, Chicken, Cow, Pig, Zebrafish
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Immunogen
Synthetic peptide within Human ProBMP2 (C terminal) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
Database link: P12643 -
Positive control
- IHC-P: Human spleen tissue. WB: HepG2 and HeLa whole cell lysate.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.01% Sodium azide
Constituents: PBS, 30% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab230498 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | 1/100. | |
| WB | 1/500 - 1/1000. Predicted molecular weight: 45 kDa. |
Target
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Relevance
ProBMP2 is the precursor of BMP2. BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. -
Cellular localization
Secreted -
Database links
- Entrez Gene: 650 Human
- Entrez Gene: 12156 Mouse
- Entrez Gene: 29373 Rat
- Omim: 112261 Human
- SwissProt: P12643 Human
- SwissProt: P21274 Mouse
- SwissProt: P49001 Rat
- Unigene: 73853 Human
see all -
Alternative names
- BMP 2 antibody
- BMP 2A antibody
- BMP2 antibody
see all
Images
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Western blot - Anti-ProBMP2 antibody (ab230498)All lanes : Anti-ProBMP2 antibody (ab230498) at 1/500 dilution
Lane 1 : HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate
Lane 2 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
Predicted band size: 45 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ProBMP2 antibody (ab230498)Formalin-fixed, paraffin-embedded human spleen tissue stained for ProBMP2 using ab230498 at 1/100 dilution in immunohistochemical analysis.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab230498 has not yet been referenced specifically in any publications.
