Anti-ProBMP2 antibody (ab230498)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-ProBMP2 antibody -
Description
Rabbit polyclonal to ProBMP2 -
Host species
Rabbit -
Specificity
ab230498 recognizes endogenous levels of BMP2 protein. -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Sheep, Rabbit, Chicken, Cow, Pig, Zebrafish
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Immunogen
Synthetic peptide within Human ProBMP2 (C terminal) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
Database link: P12643 -
Positive control
- IHC-P: Human spleen tissue. WB: HepG2 and HeLa whole cell lysate.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.3
Preservative: 0.01% Sodium azide
Constituents: PBS, 30% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab230498 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | 1/100. | |
| WB | 1/500 - 1/1000. Predicted molecular weight: 45 kDa. |
Target
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Relevance
ProBMP2 is the precursor of BMP2. BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. -
Cellular localization
Secreted -
Database links
- Entrez Gene: 650 Human
- Entrez Gene: 12156 Mouse
- Entrez Gene: 29373 Rat
- Omim: 112261 Human
- SwissProt: P12643 Human
- SwissProt: P21274 Mouse
- SwissProt: P49001 Rat
- Unigene: 73853 Human
see all -
Alternative names
- BMP 2 antibody
- BMP 2A antibody
- BMP2 antibody
see all
Images
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Western blot - Anti-ProBMP2 antibody (ab230498)All lanes : Anti-ProBMP2 antibody (ab230498) at 1/500 dilution
Lane 1 : HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate
Lane 2 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
Predicted band size: 45 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ProBMP2 antibody (ab230498)Formalin-fixed, paraffin-embedded human spleen tissue stained for ProBMP2 using ab230498 at 1/100 dilution in immunohistochemical analysis.
Datasheets and documents
References
ab230498 has not yet been referenced specifically in any publications.
