Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab32842 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500. Predicted molecular weight: 16-18 kDa.|
|IP||1/200. (1µl/250µg protein extract)|
FunctionCardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Tissue specificityBrain and also in atria, but at much lower levels than ANP.
Sequence similaritiesBelongs to the natriuretic peptide family.
- Information by UniProt
- ANFB_HUMAN antibody
- BNP antibody
- BNP(1-32) antibody
This product has been referenced in:
- Du CK et al. Survival benefit of ghrelin in the heart failure due to dilated cardiomyopathy. Pharmacol Res Perspect 2:e00064 (2014). Read more (PubMed: 25505608) »
- Li L et al. Role of brain serotonin dysfunction in the pathophysiology of congestive heart failure. J Mol Cell Cardiol : (2012). WB ; Mouse . Read more (PubMed: 22921782) »