Overview

  • Product name

    Procaine hydrochloride, Na+ channel blocker
  • Description

    Na+ channel blocker. DNA methylation inhibitor.
  • Biological description

    Na+ channel blocker (IC50 = 60-200 μM). Local anaesthetic properties in vivo. Crosses the blood-brain barrier. Inhibits DNA methylation.

    Also available in simple stock solutions (ab146726) - add 1 ml of water to get an exact, ready-to-use concentration.
  • Purity

    > 99%
  • CAS Number

    51-05-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Tada M  et al. Procaine inhibits the proliferation and DNA methylation in human hepatoma cells. Hepatol Int 1:355-64 (2007). Read more (PubMed: 19669330) »
  • Deffois A  et al. Inhibition of synaptosomal veratridine-induced sodium influx by antidepressants and neuroleptics used in chronic pain. Neurosci Lett 220:117-20 (1996). Read more (PubMed: 8981487) »
  • Usubiaga JE  et al. Relationship between the passage of local anaesthetics across the blood-brain barrier and their effects on the central nervous system. Br J Anaesth 39:943-7 (1967). Read more (PubMed: 6082561) »

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