Procarbazine hydrochloride, Clastogen and genotoxic carcinogen (ab142642)

Overview

  • Product name

    Procarbazine hydrochloride, Clastogen and genotoxic carcinogen
  • Description

    Clastogen and genotoxic carcinogen
  • Biological description

    Clastogen and genotoxic carcinogen. Induces chromosomal damage and mutations. Antineoplastic agent. Active in vivo and in vitro.
  • Purity

    > 97%
  • CAS Number

    366-70-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-[(2-Methylhydrazinyl)methyl]-N-propan-2-ylbenzamide hydrochloride
  • Molecular weight

    257.76
  • Molecular formula

    C12H19N3O.HCl
  • PubChem identifier

    9703
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C)NC(=O)C1=CC=C(C=C1)CNNC.Cl
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Phonethepswath S  et al. Flow cytometric analysis of Pig-a gene mutation and chromosomal damage induced by procarbazine hydrochloride in CD-1 mice. Environ Mol Mutagen 54:294-8 (2013). Read more (PubMed: 23427001) »
  • Amacher DE & Zelljadt I Mutagenic activity of some clastogenic chemicals at the hypoxanthine guanine phosphoribosyl transferase locus of Chinese hamster ovary cells. Mutat Res 136:137-45 (1984). Read more (PubMed: 6717480) »
  • Romagna F  et al. Micronucleus evaluation in peripheral blood reticulocytes of mice treated with procarbazine hydrochloride or mitomycin C. Mutat Res 278:197-204 (0). Read more (PubMed: 1372706) »

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