Recombinant Anti-proCNP antibody [EPR6543] (ab129096)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR6543] to proCNP
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-proCNP antibody [EPR6543]
See all proCNP primary antibodies -
Description
Rabbit monoclonal [EPR6543] to proCNP -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: IHC-P or IP -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- Human proCNP recombinant protein
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR6543 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab129096 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/10000 - 1/50000. Detects a band of approximately 6 kDa (predicted molecular weight: 13 kDa).
NOTE: ab129096 has only been tested against the recombinant protein . |
Notes |
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WB
1/10000 - 1/50000. Detects a band of approximately 6 kDa (predicted molecular weight: 13 kDa). NOTE: ab129096 has only been tested against the recombinant protein . |
Target
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Function
Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3. -
Sequence similarities
Belongs to the natriuretic peptide family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 4880 Human
- Entrez Gene: 18159 Mouse
- Entrez Gene: 114593 Rat
- Omim: 600296 Human
- SwissProt: P23582 Human
- SwissProt: Q61839 Mouse
- SwissProt: P55207 Rat
- Unigene: 247916 Human
see all -
Alternative names
- ANFC_HUMAN antibody
- C type natriuretic peptide precursor antibody
- CNP antibody
see all
Images
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Anti-proCNP antibody [EPR6543] (ab129096) at 1/10000 dilution + Human proCNP recombinant protein at 0.01 µg
Secondary
HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 13 kDa
Observed band size: 6 kDa why is the actual band size different from the predicted?
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab129096 has not yet been referenced specifically in any publications.