Overview

  • Product name

    Prodigiosin, apoptotic agent
  • Description

    Potent apoptotic agent. Antibiotic agent.
  • Biological description

    Potent apoptotic agent. Antibiotic agent. Induces caspase-dependent apoptosis. Inhibits mTORC1 and mTORC2. Reactivates p53. Inhibits iNOS expression. Shows anti-ischemic and antimalarial effects in vivo.
  • Purity

    > 95%
  • CAS Number

    82-89-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Hong B  et al. Prodigiosin rescues deficient p53 signaling and antitumor effects via upregulating p73 and disrupting its interaction with mutant p53. Cancer Res 74:1153-65 (2014). Read more (PubMed: 24247721) »
  • Chang CC  et al. Prodigiosin inhibits gp91(phox) and iNOS expression to protect mice against the oxidative/nitrosative brain injury induced by hypoxia-ischemia. Toxicol Appl Pharmacol 257:137-47 (2011). Read more (PubMed: 21925195) »
  • Ohkuma S  et al. Prodigiosins uncouple lysosomal vacuolar-type ATPase through promotion of H+/Cl- symport. Biochem J 334 ( Pt 3):731-41 (1998). Read more (PubMed: 9729483) »

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