Mitochondrial Staining Reagent - Red - Cytopainter (ab176832)
Overview
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Product name
Mitochondrial Staining Reagent - Red - Cytopainter
See all Mitochondria kits -
Sample type
Adherent cells, Suspension cells -
Assay type
Cell-based (qualitative) -
Species reactivity
Reacts with: Mammals, Other species -
Product overview
Abcam's Mitochondrial Staining Reagent - Red | Cytopainter (ab176832) is part of a series of new fluorogenic probes to label mitochondria of live cells. The proprietary mitochondria dye selectively accumulates in mitochondria probably via the mitochondrial membrane potential gradient. The mitochondrial indicator is a hydrophobic compound that easily permeates intact live cells and becomes trapped in mitochondria after it gets into cells. The fluorescent mitochondrial indicator is retained in mitochondria for a long time since it carries a cell-retaining group. This key feature significantly increases the staining efficiency; make it useful for a variety of studies, including cell adhesion, chemotaxis, multidrug resistance, cell viability, apoptosis and cytotoxicity.
Review other dyes and kits for mitochondrial staining, or the live cell staining fluorescent dyes guide
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Notes
Mitochondria are membrane-enclosed organelles found in most eukaryotic cells. Mitochondria are sometimes described as “cellular power plants” because they generate most of the cellular supply of ATP. In addition to supplying cellular energy, mitochondria are involved in a range of other processes, such as signaling, cellular differentiation, cell death, as well as the control of the cell cycle and cell growth. Mitochondria have been implicated in several human diseases, including mitochondrial disorders and cardiac dysfunction, and may play a role in the aging process. Although most of a cellular DNA is contained in the cell nucleus, the mitochondrion has its own independent genome.
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Platform
Fluorescence microscope
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components 500 tests CytoPainter MitoRed Indicator Reagent 1 x 500 tests -
Research areas
Associated products
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Corresponding kit
Images
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U2OS cells stained with ab176832
Image of U2OS cells stained with Abcam's CytoPainter MitoRed Indicator Reagent (ab176832) in a Costar black wall/clear bottom 96-well plate.
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Excitation and Emission spectra for CytoPainter MitoRed Indicator Reagent (ab176832)
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab176832 has been referenced in 2 publications.
- Kant S et al. PGC1a Regulates the Endothelial Response to Fluid Shear Stress via Telomerase Reverse Transcriptase Control of Heme Oxygenase-1. Arterioscler Thromb Vasc Biol 42:19-34 (2022). PubMed: 34789002
- Harder I et al. Dysregulated PI3K Signaling in B Cells of CVID Patients. Cells 11:N/A (2022). PubMed: 35159274