(+)-Bicuculline, GABAA antagonist (ab120107)
Key features and details
- GABAA antagonist
- CAS Number: 485-49-4
- Soluble in ethanol to 5 mM and DMSO to 100 mM (with heating)
- Form / State: Solid
- Source: Synthetic
Product name(+)-Bicuculline, GABAA antagonist
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol to 5 mM and DMSO to 100 mM (with heating)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120107 has been referenced in 34 publications.
- Mishra P & Narayanan R Conjunctive changes in multiple ion channels mediate activity-dependent intrinsic plasticity in hippocampal granule cells. iScience 25:103922 (2022). PubMed: 35252816
- Schröter M et al. Functional imaging of brain organoids using high-density microelectrode arrays. MRS Bull 47:530-544 (2022). PubMed: 36120104
- Blazon M et al. N-type calcium channels control GABAergic transmission in brain areas related to fear and anxiety. OBM Neurobiol 5:N/A (2021). PubMed: 33521586
- Dingle YL et al. Integrated functional neuronal network analysis of 3D silk-collagen scaffold-based mouse cortical culture. STAR Protoc 2:100292 (2021). PubMed: 33537680
- Malik AR et al. SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology. Cell Rep 26:2792-2804.e6 (2019). PubMed: 30840898