1-Deoxynojirimycin, alpha-glycosidase inhibitor (ab144834)
Key features and details
- Potent α-glycosidase inhibitor. Antihyperglycemic agent.
- CAS Number: 19130-96-2
- Purity: > 98%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Streptomyces sp.
Overview
-
Product name
1-Deoxynojirimycin, alpha-glycosidase inhibitor -
Description
Potent α-glycosidase inhibitor. Antihyperglycemic agent. -
Biological description
Potent α-glycosidase inhibitor (IC50 = 30 nM). Antihyperglycemic agent. Downregulates SGLT1, Na+/K+-ATP and GLUT2 expression. Decreases MCP-1 and TNF-α levels. Shows antidiabetic, antiviral, antiobesity and anti-inflammatory effects in vivo. Orally active. -
Purity
> 98% -
CAS Number
19130-96-2 -
Chemical structure
Properties
-
Chemical name
(2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol -
Molecular weight
163.17 -
Molecular formula
C6H13NO4 -
PubChem identifier
29435 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C1[C@@H]([C@H]([C@@H]([C@H](N1)CO)O)O)O -
Source
Streptomyces sp.
-
Research areas
Images
-
Chemical Structure - 1-Deoxynojirimycin, alpha-glycosidase inhibitor (ab144834)2D chemical structure image of ab144834, 1-Deoxynojirimycin, alpha-glycosidase inhibitor
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab144834 has not yet been referenced specifically in any publications.