1,10-Phenanthroline, Metalloprotease inhibitor (ab141196)
Key features and details
- Membrane permeable chelating agent. Metalloprotease inhibitor.
- CAS Number: 66-71-7
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
1,10-Phenanthroline, Metalloprotease inhibitor -
Description
Membrane permeable chelating agent. Metalloprotease inhibitor. -
Biological description
Membrane permeable chelating agent. Metalloprotease inhibitor. Chelates intracellular heavy metals including zinc, copper and iron. Binds DNA and modulates multiple signaling pathways in vitro and in vivo.
-
Purity
> 99% -
CAS Number
66-71-7 -
Chemical structure
Properties
-
Chemical name
1,10-Phenanthroline -
Molecular weight
180.21 -
Molecular formula
C12H8N2 -
PubChem identifier
1318 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
c1ccnc3c1ccc2cccnc23 -
Source
Synthetic
-
Research areas
- Epigenetics and Nuclear Signaling
- DNA / RNA
- DNA Damage & Repair
- DNA Damage Response
- DNA Damage Recognition
- Epigenetics and Nuclear Signaling
- Transcription
- Domain Families
- HLH / Leucine Zipper
- Helix-Turn-Helix
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Retinoic & Retinoid
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Orphan Nuclear Receptors
- Epigenetics and Nuclear Signaling
- Chromatin Modifying Enzymes
- Acetylation
- HDACs
- Class II / Hda1 Class
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Molecular processes
- Mitochondrial transcription
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
Images
-
Chemical Structure - 1,10-Phenanthroline, Metalloprotease inhibitor (ab141196)2D chemical structure image of ab141196, 1,10-Phenanthroline, Metalloprotease inhibitor
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab141196 has not yet been referenced specifically in any publications.