2-Deoxy-D-glucose, glucose analog (ab142242)
Key features and details
- Non-metabolizable glucose analog and glycolytic inhibitor. Antitumor agent.
- CAS Number: 154-17-6
- Purity: > 97%
Soluble in Water >15 mg/mL or DMSO >15 mg/mL.
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
2-Deoxy-D-glucose, glucose analog -
Description
Non-metabolizable glucose analog and glycolytic inhibitor. Antitumor agent. -
Purity
> 97% -
CAS Number
154-17-6 -
Chemical structure
Properties
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Chemical name
(4R,5S,6R)-6-(Hydroxymethyl)oxane-2,4,5-triol
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Molecular weight
164.16 -
PubChem identifier
439268 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in Water >15 mg/mL or DMSO >15 mg/mL.
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1C(C(C(OC1O)CO)O)O -
Source
Synthetic
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Research areas
Images
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Chemical Structure - 2-Deoxy-D-glucose, glucose analog (ab142242)2D chemical structure image of ab142242, 2-Deoxy-D-glucose, glucose analog
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (4)
ab142242 has been referenced in 4 publications.
- Wang Z et al. The Fibrillin-1/VEGFR2/STAT2 signaling axis promotes chemoresistance via modulating glycolysis and angiogenesis in ovarian cancer organoids and cells. Cancer Commun (Lond) 42:245-265 (2022). PubMed: 35234370
- Blancke Soares A et al. High-resolution spatiotemporal pHe and pO2 imaging in head and neck and oesophageal carcinoma cells. Cancer Metab 9:21 (2021). PubMed: 33947450
- Morein D et al. Continuous Inflammatory Stimulation Leads via Metabolic Plasticity to a Prometastatic Phenotype in Triple-Negative Breast Cancer Cells. Cells 10:N/A (2021). PubMed: 34072893
- Cabezas-Cruz A et al. Anaplasma phagocytophilum Infection Subverts Carbohydrate Metabolic Pathways in the Tick Vector, Ixodes scapularis. Front Cell Infect Microbiol 7:23 (2017). PubMed: 28229048
