Key features and details
- Non-selective myosin ATPase inhibitor
- CAS Number: 57-71-6
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Product name2,3-Butanedione 2-monoxime (BDM), Non-selective myosin ATPase inhibitor
DescriptionNon-selective myosin ATPase inhibitor
- Biacetyl monoxime
- Diacetyl monoxime
Non-selective myosin ATPase inhibitor (Ki = 5 mM at myosin II). Potent Kv2.1 (DRK1) and L-Type Ca2+ channel inhibitor (Ki and IC50 values are 10.7 nM and 5.8 mM, respectively). Blood-brain barrier permeable. Inhibits muscle contraction.
Chemical name2,3-Butanedione monoxime
Storage instructionsStore at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120616 has been referenced in 2 publications.
- Cornean A et al. Precise in vivo functional analysis of DNA variants with base editing using ACEofBASEs target prediction. Elife 11:N/A (2022). PubMed: 35373735
- Gerbin KA et al. Cell states beyond transcriptomics: Integrating structural organization and gene expression in hiPSC-derived cardiomyocytes. Cell Syst 12:670-687.e10 (2021). PubMed: 34043964