Key features and details
- Ionotropic receptor antagonist
- CAS Number: 46026-75-9
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Product name2,3 cis-Piperidine dicarboxylic acid (cis PDA), Ionotropic receptor antagonist
DescriptionIonotropic receptor antagonist
- cis PDA
General ionotropic receptor antagonist. Blocks NMDA, AMPA and kainate mediated responses. Also acts as a partial NMDA receptor agonist in the in vitro rat cerebellar cGMP model.
Also available in simple stock solutions (ab146697) - add 1 ml of water to get an exact, ready-to-use concentration.
Chemical namecis-Piperidine-2,3-dicarboxylic acid
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Receptors & Transporters
- Broad spectrum / non-selective
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120038 has been referenced in 1 publication.
- Umino Y et al. Rod Photoresponse Kinetics Limit Temporal Contrast Sensitivity in Mesopic Vision. J Neurosci 39:3041-3056 (2019). PubMed: 30737308