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    products/biochemicals/9-cis-retinoic-acid-endogenous-retinoic-acid-receptor-agonist-ab141023.pdf

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9-cis-Retinoic acid, Endogenous retinoic acid receptor agonist (ab141023)

  • Datasheet
  • SDS
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Chemical Structure - 9-cis-Retinoic acid, Endogenous retinoic acid receptor agonist (ab141023)

    Key features and details

    • High affinity, endogenous retinoic acid receptor agonist
    • CAS Number: 5300-03-8
    • Purity: > 98%
    • Soluble in DMSO to 25 mM and in ethanol to 25 mM
    • Form / State: Solid
    • Source: Synthetic

    Overview

    • Product name

      9-cis-Retinoic acid, Endogenous retinoic acid receptor agonist
    • Description

      High affinity, endogenous retinoic acid receptor agonist
    • Purity

      > 98%
    • CAS Number

      5300-03-8
    • Chemical structure

      Chemical Structure

    Properties

    • Chemical name

      3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)nona-2E,4E,6Z,8E-tetraenoic acid
    • Molecular weight

      300.44
    • Molecular formula

      C20H28O2
    • PubChem identifier

      449171
    • Storage instructions

      Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. The product can be stored for up to 12 months.
    • Solubility overview

      Soluble in DMSO to 25 mM and in ethanol to 25 mM
    • Handling

      Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

      Toxic, refer to SDS for further information.

      Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

    • SMILES

      CC=1CCCC(C)(C)C=1/C=C/C(/C)=C\C=C\C(\C)=C\C(=O)O
    • Source

      Synthetic

    • Research areas

      • Cell Biology
      • Apoptosis
      • Nucleus
      • Other
      • Cardiovascular
      • Lipids / Lipoproteins
      • Lipid Metabolism
      • Cholesterol Metabolism
      • Epigenetics and Nuclear Signaling
      • Transcription
      • Domain Families
      • Zinc Finger
      • Signal Transduction
      • Signaling Pathway
      • Lipid Signaling
      • Other
      • Signal Transduction
      • Signaling Pathway
      • Nuclear Signaling
      • Nuclear Hormone Receptors
      • Estrogen
      • Signal Transduction
      • Signaling Pathway
      • Nuclear Signaling
      • Nuclear Hormone Receptors
      • Retinoic & Retinoid
      • Neuroscience
      • Endocrine system
      • Gonadotrophic axis
      • Epigenetics and Nuclear Signaling
      • Nuclear Signaling Pathways
      • Nuclear Receptors
      • Co-activators/co-repressors
      • Epigenetics and Nuclear Signaling
      • Nuclear Signaling Pathways
      • Nuclear Receptors
      • Estrogen
      • Epigenetics and Nuclear Signaling
      • Nuclear Signaling Pathways
      • Nuclear Receptors
      • Retinoic & Retinoid
      • Epigenetics and Nuclear Signaling
      • Transcription
      • Other factors
      • Epigenetics and Nuclear Signaling
      • Transcription
      • Co-factors
      • Epigenetics and Nuclear Signaling
      • Nuclear Signaling Pathways
      • Nuclear Receptors
      • Orphan Nuclear Receptors
      • Signal Transduction
      • Metabolism
      • Lipid metabolism
      • Cancer
      • Signal transduction
      • Nuclear signaling
      • Nuclear hormone receptors
      • Estrogen
      • Cancer
      • Signal transduction
      • Nuclear signaling
      • Nuclear hormone receptors
      • Retanoic and retanoid
      • Cancer
      • Tumor biomarkers
      • Receptors
      • Cancer
      • Invasion/microenvironment
      • Apoptosis
      • Other
      • Cancer
      • Cancer Metabolism
      • Metabolic signaling pathway
      • Metabolism of lipids and lipoproteins
      • Biochemicals
      • Chemical Type
      • Biochemicals
      • Biochemicals
      • Pharmacology
      • Receptors & Transporters
      • Nuclear Receptors
      • Retinoic acid receptors
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Lipid and lipoprotein metabolism
      • Lipid metabolism
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Lipid and lipoprotein metabolism
      • Cholesterol Metabolism
      • Metabolism
      • Pathways and Processes
      • Cofactors, Vitamins / minerals
      • Co-factors
      • Biochemicals
      • Research Area
      • Cancer
      • Nuclear Receptors
      • Retinoic acid receptors
      • Biochemicals
      • Research Area
      • Heart disease
      • Nuclear Receptors
      • Retinoic acid receptors
      • Biochemicals
      • Research Area
      • Hypertension
      • Nuclear Receptors
      • Retinoic acid receptors
      • Biochemicals
      • Research Area
      • Stroke
      • Nuclear Receptors
      • Retinoic acid receptors
      • Cancer
      • Cell Death
      • Apoptosis
      • Other
      • Cancer
      • Cell Death
      • Apoptosis
      • Nucleus
      • Other

    Images

    • Chemical Structure - 9-cis-Retinoic acid, Endogenous retinoic acid receptor agonist (ab141023)
      Chemical Structure - 9-cis-Retinoic acid, Endogenous retinoic acid receptor agonist (ab141023)
      2D chemical structure image of ab141023, 9-cis-Retinoic acid, Endogenous retinoic acid receptor agonist

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (1)

    Publishing research using ab141023? Please let us know so that we can cite the reference in this datasheet.

    ab141023 has been referenced in 1 publication.

    • Zhao H  et al. Intranasal delivery of 9-cis retinoic acid reduces beta-amyloid deposition via inhibiting astrocyte-mediated inflammation. Aging (Albany NY) 12:5469-5478 (2020). PubMed: 32209731

    Customer reviews and Q&As

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