AG 1478, EGF receptor tyrosine kinase inhibitor (ab141438)
Key features and details
- Selective EGF receptor tyrosine kinase inhibitor
- CAS Number: 175178-82-2
- Purity: > 98%
- Soluble in ethanol to 25 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameAG 1478, EGF receptor tyrosine kinase inhibitor
DescriptionSelective EGF receptor tyrosine kinase inhibitor
Selective EGF receptor tyrosine kinase inhibitor (Ki = 10 nM). Supresses proliferation and cell-cycle progression. Cell-permeable and active in vivo.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol to 25 mM and in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Receptors & Transporters
- Enzyme-Linked Receptors
- Receptor tyrosine kinases
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141438 has been referenced in 1 publication.
- Chang KW et al. Establishment of a p53 Null Murine Oral Carcinoma Cell Line and the Identification of Genetic Alterations Associated with This Carcinoma. Int J Mol Sci 21:N/A (2020). PubMed: 33302499