Albendazole, Microtubule depolymerizing agent (ab141241)
Key features and details
- Microtubule depolymerizing agent; affects tubulin dynamics
- CAS Number: 54965-21-8
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Albendazole, Microtubule depolymerizing agent -
Description
Microtubule depolymerizing agent; affects tubulin dynamics -
Biological description
Anthelmintic benzimidazole and microtubule depolymerizing agent. Able to inhibit brain microtubule polymerization in vitro and delays microtubule assembly in vivo. Anti-tumour activity seen in vivo.
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Purity
> 98% -
CAS Number
54965-21-8 -
Chemical structure
Properties
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Chemical name
N-[6-(Propylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester -
Molecular weight
265.33 -
Molecular formula
C12H15N3O2S -
PubChem identifier
2082 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(OC)Nc1nc2ccc(cc2n1)SCCC -
Source
Synthetic
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Research areas
- Epigenetics and Nuclear Signaling
- Transcription
- Domain Families
- HLH / Leucine Zipper
- Helix-Turn-Helix
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Retinoic & Retinoid
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Orphan Nuclear Receptors
- Epigenetics and Nuclear Signaling
- Chromatin Modifying Enzymes
- Acetylation
- HDACs
- Class II / Hda1 Class
Images
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Chemical Structure - Albendazole, Microtubule depolymerizing agent (ab141241)2D chemical structure image of ab141241, Albendazole, Microtubule depolymerizing agent
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab141241 has not yet been referenced specifically in any publications.