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    products/biochemicals/aminoguanidine-hydrochloride-nos-inhibitor-ab120123.pdf

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Neuroscience Neurotransmission Nitric Oxide NOS
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Aminoguanidine hydrochloride, NOS inhibitor (ab120123)

  • Datasheet
  • SDS
  • COA
Submit a review Q&A (1)References (2)

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Chemical Structure - Aminoguanidine hydrochloride, NOS inhibitor (ab120123)

    Key features and details

    • NOS inhibitor
    • CAS Number: 1937-19-5
    • Soluble in water to 100 mM
    • Form / State: Solid
    • Source: Synthetic

    Overview

    • Product name

      Aminoguanidine hydrochloride, NOS inhibitor
    • Description

      NOS inhibitor
    • Biological description

      Irreversible inhibitor of iNOS, displaying 26-fold selectivity over nNOS. In vitro and in vivo inhibitor of the formation of glycosylation end products associated with diabetes and aging.

    • CAS Number

      1937-19-5
    • Chemical structure

      Chemical Structure

    Properties

    • Chemical name

      Guanylhydrazine hydrochloride
    • Molecular weight

      110.55
    • Molecular formula

      CH6N4.HCl
    • PubChem identifier

      16017
    • Storage instructions

      Store at Room Temperature. The product can be stored for up to 12 months.
    • Solubility overview

      Soluble in water to 100 mM
    • Handling

      Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

      Refer to SDS for further information

      Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

    • SMILES

      Cl.N=C(N)NN
    • Source

      Synthetic

    • Research areas

      • Neuroscience
      • Neurotransmission
      • Nitric Oxide
      • NOS
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      • Biochemicals
      • Research Area
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      • Nitric oxide & oxidative stress
      • NOS
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    Images

    • Chemical Structure - Aminoguanidine hydrochloride, NOS inhibitor (ab120123)
      Chemical Structure - Aminoguanidine hydrochloride, NOS inhibitor (ab120123)
      2D chemical structure image of ab120123, Aminoguanidine hydrochloride, NOS inhibitor

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download
    • COA

    References (2)

    Publishing research using ab120123? Please let us know so that we can cite the reference in this datasheet.

    ab120123 has been referenced in 2 publications.

    • Skinner SC  et al. Increased Prevalence of Type 2 Diabetes-Related Complications in Combined Type 2 Diabetes and Sickle Cell Trait. Diabetes Care 41:2595-2602 (2018). PubMed: 30327363
    • Zhang Q  et al. Inhibition of cytoskeletal protein carbonylation may protect against oxidative damage in traumatic brain injury. Exp Ther Med 12:4107-4112 (2016). PubMed: 28101189

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    Question

    Serait-il possible d’obtenir la fiche MSDS de la référence ab120123, s’il vous plait ?

    Read More

    Abcam community

    Verified customer

    Asked on Oct 10 2012

    Answer

    Merci de nous avoir contactés.

    La fiche MSDS du ab120123 (Aminoguanidine hydrochloride) est disponible depuis la fiche technique du produit ou via ce lien : https://www.abcam.com/ps/Products/120/ab120123/Msds/ab120123_CLP1_EN.pdf

    J'espère que ces informations vous seront utiles. N'hésitez pas à nous contacter de nouveau si vous avez d'autres questions.

    Read More

    Abcam Scientific Support

    Answered on Oct 10 2012

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
    For licensing inquiries, please contact partnerships@abcam.com

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