Angiotensin II (human), Vasoconstrictor peptide (ab120183)
Key features and details
- Vasoconstrictor peptide
- CAS Number: 4474-91-3
- Soluble in water to 1mg/ml
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Angiotensin II (human), Vasoconstrictor peptide -
Description
Vasoconstrictor peptide -
Biological description
Endogenous peptide involved in body water and electrolyte homeostasis, blood pressure, cyclicity of reproductive hormones and sexual behaviours, and the regulation of pituitary gland hormones.
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CAS Number
4474-91-3 -
Chemical structure
Properties
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Molecular weight
1046.18 -
Molecular formula
C50H71N13O12 -
Sequence
DRVYIHPF -
PubChem identifier
172198 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 1mg/ml -
Handling
This product is supplied in one (or more) pack size which is freeze dried. Therefore the contents may not be readily visible, as they can coat the bottom or walls of the vial. Please see our FAQs and information page for more details on handling.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
Images
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Chemical Structure - Angiotensin II (human), Vasoconstrictor peptide (ab120183)2D chemical structure image of ab120183, Angiotensin II (human), Vasoconstrictor peptide
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (12)
ab120183 has been referenced in 12 publications.
- Guo J et al. Metformin protects against abdominal aortic aneurysm by Atg7-induced autophagy. Adv Clin Exp Med 31:59-69 (2022). PubMed: 34714980
- Wang L et al. Adropin inhibits the phenotypic modulation and proliferation of vascular smooth muscle cells during neointimal hyperplasia by activating the AMPK/ACC signaling pathway. Exp Ther Med 21:560 (2021). PubMed: 33850532
- Bao Q et al. Intermittent hypoxia mediated by TSP1 dependent on STAT3 induces cardiac fibroblast activation and cardiac fibrosis. Elife 9:N/A (2020). PubMed: 31934850
- Yang S et al. The role of STAT3/mTOR-regulated autophagy in angiotensin II-induced senescence of human glomerular mesangial cells. Cell Signal 53:327-338 (2019). PubMed: 30389500
- Duan J et al. The cell-wide web coordinates cellular processes by directing site-specific Ca2+ flux across cytoplasmic nanocourses. Nat Commun 10:2299 (2019). PubMed: 31127110