ATP disodium salt, P2 receptor agonis (ab120385)
Key features and details
- P2 receptor agonist. Signalling molecule.
- CAS Number: 34369-07-8
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
ATP disodium salt, P2 receptor agonis -
Description
P2 receptor agonist. Signalling molecule. -
Biological description
Purinergic P2 receptor agonist. (EC50 values are 0.60 (P2X1), 1.3 (P2X3), 9.1 (P2X4) and 0.5 μM (P2X5)). Involved in extracellular signalling as a cotransmitter in all nerves, in both the central and peripheral nervous systems.
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CAS Number
34369-07-8 -
Chemical structure
Properties
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Chemical name
Adenosine 5'-triphosphate disodium salt -
Molecular weight
551.14 -
Molecular formula
C10H14N5Na2O13P3 -
PubChem identifier
13803 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=P(O)(O[Na])OP(=O)(O[Na])OP(=O)(O)OC[C@H]3O[C@@H](n2cnc1c(N)ncnc12)[C@H](O)[C@@H]3O -
Source
Synthetic
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Research areas
Images
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Chemical Structure - ATP disodium salt, P2 receptor agonis (ab120385)2D chemical structure image of ab120385, ATP disodium salt, P2 receptor agonis
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (2)
ab120385 has been referenced in 2 publications.
- Dyer MS et al. Mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex. J Neurochem 157:1300-1315 (2021). PubMed: 33064315
- Toulme E et al. P2X4 receptors in activated C8-B4 cells of cerebellar microglial origin. J Gen Physiol 135:333-53 (2010). PubMed: 20231374